The Effectiveness Of Pilocarpine On Opioid-Induced Xerostomia – A Systematic Review

Authors

  • Bianca Mary Jacob, S. Shree Lakshmi, Sindhu R., D. Prabu, Raj Mohan, M. Dinesh Dhamodhar, Bharathwaj V.V.

Abstract

Background: Pilocarpine is a widely prescribed medication for relieving Xerostomia caused especially due to radiation exposure and other systemic diseases.

Aim: To assess the effectiveness of Pilocarpine on opioid-induced Xerostomia.

Study Design: A systematic review of research articles was carried out. Electronic and hand search results revealed 243 articles, out of which 235 articles were screened. The intervention and outcomes were assessed in the studies included for the review.

Results: Four studies were included in this systematic review. These studies assessed the role of Pilocarpine in relieving opioid-induced Xerostomia in terms of efficiency and effectiveness.

Conclusion: From the four included articles, it is evident that Pilocarpine significantly relieves Xerostomia caused due to opioids, with either minimal or no side effects.

 

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Published

2021-08-18

How to Cite

Bianca Mary Jacob, S. Shree Lakshmi, Sindhu R., D. Prabu, Raj Mohan, M. Dinesh Dhamodhar, Bharathwaj V.V. (2021). The Effectiveness Of Pilocarpine On Opioid-Induced Xerostomia – A Systematic Review. Drugs and Cell Therapies in Hematology, 10(1), 1511–1521. Retrieved from http://dcth.org/index.php/journal/article/view/293

Issue

Vol. 10 No. 1 (2021)

Section

Articles