Intervention Of Topical Fluorouracil Treatment On Actinic Keratosis -A Systematic Review

Authors

  • Prashanthy.M. R, Prabu.D, Suganya.P,Rajmohan.M, Dinesh Damodhar, Bharathwaj.V.V, Sindhu.R, Shreelakshmi.S

Abstract

AIM

To assess the effectiveness of topical Fluorouracil as one of the interventions for Actinic Keratosis.

STUDY DESIGN

A systematic review of controlled trials, clinical trials, and a pilot study was performed. Electronic and hand searches retrieved 4620 records.533 were screened. Six studies were included in the systematic review.Study included in the systematic review examined the intervention and outcomes.

RESULTS

Six studies were included in this systematic review, which were randomized controlled trials and pilot studies. There were studies performed in different countries. Among the six trials, two were found statistically significant, but further studies should be done to prove the effectiveness of topical Fluorouracil for Actinic keratoses.

 CONCLUSION

There is a dearth of substantiation to show the efficacy of topical Fluorouracil for Actinic keratosis. Therefore, further Pilot studies and control trials should be done to assess the efficacy of topical Fluorouracil for Actinic keratosis.

Published

2021-09-01

How to Cite

Prashanthy.M. R, Prabu.D, Suganya.P,Rajmohan.M, Dinesh Damodhar, Bharathwaj.V.V, Sindhu.R, Shreelakshmi.S. (2021). Intervention Of Topical Fluorouracil Treatment On Actinic Keratosis -A Systematic Review. Drugs and Cell Therapies in Hematology, 10(1), 1793–1804. Retrieved from http://dcth.org/index.php/journal/article/view/340

Issue

Section

Articles