Antibiotic susceptibility pattern of clinical Acinetobacter isolates in a teritay care centre

Abstract

Acinetobacter is an opportunistic pathogen which is associated with high fatal rate in hospitalized patients due to multidrug resistance among these isolates with limited cure option. The present study was done to determine the   antibiotic susceptibility pattern of Acinetobacter species in various samplesfrom both inpatients and outpatients attending a tertiary care. The sensitivity patterns were analyzed from various clinical specimens obtained from both in-patients and outpatients of a teaching hospital.The isolates were recovered from Nutrient agar, sheep blood agar and Mac Conkey agar and then identification was done by standard biochemical test, antibiogram was obtained by disc diffusion method. Acinetobacter isolates were obtained more from wound sample. All the isolates were susceptible to Tigecycline and colistin.About 60-80 % of isolates were resistance to third and fourth generation cephalosporins and 45-55 % of isolates were resistance to carbapenem.  Hence the combination of colistin and tigecycline with other antibiotics seems to be the rational treatment options for treating MDR Acinetobacter isolates.