Impact of Serum Vitamin D Levels on Asthma Control in Children: A Cross-Sectional Study

Abstract

Aim: To assess the impact of serum vitamin D levels on asthma control in children:

Study design: A cross-sectional study

Place and Duration: This study was conducted at Teaching Hospital Turbat/Mekran Medical College Turbat Pakistan.from April 2019 to May 2020.

Methodology: The 60 children of ages between 5 to 18 years with persistent asthma and taking preventive therapy for more than 3 months were enrolled in this study. The sociodemographic, clinical, and biochemical data were collected in a pre-designed questionnaire. The serum vitamin D and IgE levels were determined. The collected data were analyzed by SPSS version 23.0. The chi-square test was used to determine the statistical difference among groups.

Results: Out of 60 asthma children, 26 patients had well-controlled asthma, 22 had partially controlled, and 12 had poorly controlled asthma. There was no association found between asthma control with age, gender, family history, birth weight, and serum IgE levels. Insufficient or deficient serum vitamin D levels have been statistically correlated with asthma control in children. The vitamin D deficient children had un-controlled and poorly controlled asthma compared to the children with sufficient serum vitamin D.

Conclusion: In conclusion, insufficient serum vitamin D is found as a suboptimal modifiable factor for the control of asthma in children.